Technological developments

Besides our strong research in protein engineering, we also engage in the development of infrastructure for optoacoustic spectroscopy and screening. For example, we developed a three-modality spectrometer allowing us to read the absorbance, fluorescence and optoacoustics spectra of a sample providing insight into its photophysics and new vantage points for the development of the agents.

optoacoustic photoacoustic
fluorescence screening

Further reading:

  1. Fuenzalida Werner JP, Huang Y, Mishra K, Janowski R, Vetschera P, Heichler C, Chmyrov A, Neufert C, Niessing D, Ntziachristos V, Stiel AC. Challenging a Preconception: Optoacoustic Spectrum Differs from the Optical Absorption Spectrum of Proteins and Dyes for Molecular Imaging. Chem. 2020. 92(15):10717-10724
  1. Seeger M, Stiel AC*, Ntziachristos V*. In vitro optoacoustic flow cytometry with light scattering referencing. Sci Rep. 11(1):2181